cattle, pigs, horses, racoons, porcupines, domesticated dogs) or their body fluids (especially urine) via water or soil contamination. The primary mode of human transmission is direct or indirect contact with infected animals (e.g. Both anterior and posterior segment ophthalmic manifestations can occur in Leptospirosis and this Eyewiki emphasizes these ocular findings. Weil disease is the late icteric phase following severe systemic manifestations including interstitial nephritis, uremia, oliguria, kidney lesions, vascular injury, meningitis, jaundice, psychosis, confusion, and delirium. The majority of cases present with the acute (anicteric) phase consisting of self-limiting clinical manifestations including sudden fever, myalgia, headache, scleral icterus, chemosis, nausea, anorexia, and abdominal pain. This tropical disease is the most common zoonotic illness worldwide.
Leptospirosis (Weil disease) is a gram-negative, water-borne, spirochete that is part of the Leptospira genus within the Leptospiraceae family.
